Tottenham have suffered a third loss in a row, after going down 1-nil to Chelsea at home.
Jorginho's penalty in the 34th minute, after Eric Dier had fouled Timo Werner, was enough for the guests to seal their first away victory under Thomas Tuchel.
The win elevated the London Blues to 4th in the standings, with 36 points from 22 matches, eleven points shy of leaders Manchester City, who have a game in hand.
Meanwhile, Jose Mourinho has suffered his first ever back-to-back home loss, with his side moving down to 8th, with 33 points from 21 outings.